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HOME > Staff > MIYAMOTO

 Education

• 1965  B.S. Department of Chemical Engineering, Faculty of Engineering, Kyoto University
• 1967  M.S. Department of Chemical Engineering, Graduate School of Engineering, Kyoto University

 Degrees

• 1967  M.S. in Engineering, Kyoto University
• 1978  Ph.D. in Engineering, Osaka University

 Posts

• 1967  Research Associate, Faculty of Pharmaceutical Sciences, Osaka University
• 1977  Visiting Scholar, University of California at Berkeley, USA (-1979)
• 1983  Associate Professor, Faculty of Pharmaceutical Sciences, Osaka University
• 1987  Visiting Scholar, Georgia Institute of Technology, USA
• 1992  Professor, Faculty of Pharmaceutical Sciences, Osaka University
• 1998  Professor, Graduate School of Pharmaceutical Sciences, Osaka University
• 1999  Member of University Council (-2001)
• 2001  Dean, Graduate School of Pharmaceutical Sciences, Osaka University (-2003)
• 2005  Professor Emeritus
• 2005  Specially Appointed Professor, International Center for Biotechnology, Osaka University
• 2006  Specially Appointed Professor, Osaka University Bangkok Center for Education and Research
• 2007  Specially Appointed Professor, Global Collaboration Center, Osaka University

 Field of Research

• Environmental Biotechnology, Microalgal Biotechnology

 Research Interests

• Phycoremediation of Polluted Environments, System Development for biomaterials and biofuel production

 Keywords

• Biofuels, Biomass, Bioremediation, Green technology, Mass cultivation, Microalgae, Microorganisms

 Membership of Professional Associations

• The Society for Biotechnology, Japan / Japan Society for Environmental Biotechnology / The Pharmaceutical Society of Japan / Japanese Society of Enzyme Engineering

 Publications and Presentations

 Books

• Renewable biological systems for alternative sustainable energy production
  Miyamoto, K.
  "FAO Agricultural Services Bulletin" (edited by K. Miyamoto), Food and Agriculture Organization of the United Nation, pp. 1-5 (1997).
• Algal CO₂ -fixation and H₂ photoproduction
  Ike, A., K. Yoshihara, H. Nagase, K. Hirata, K. Miyamoto
  "BioHydrogen" (edited by O.R. Zaborsky et al.), Plenum Press, New York, pp. 311-318 (1998).
• Hydrogen photoproduction from starch in CO₂ -fixing microalgal biomass by a halotolerant bacterial community
  Ike, A., N. Toda, T. Murakawa, K. Hirata, K. Miyamoto
  "BioHydrogen" (edited by O.R. Zaborsky et al.), Plenum Press, New York, pp. 265-271 (1998).
• Hydrogen photoproduction from starch in algal biomass
  Ike, A., H. Kawaguchi, K. Hirata, K. Miyamoto
  "BIOHYDROGEN II" (edited by J. Miyake et al.), PERGAMON, Amsterdam, pp. 53-61 (2001).
• Microbial biotechnology for clean environments -Simultaneous removal of CO₂ and NOx by microalgal culture-
  Miyamoto, K., H. Nagase, K. Hirata
  "Photosynthetic Microorganisms in Environmental Biotechnology" (edited by H. Kojima, H. and Y.K. Lee), Springer-Verlag, Hong Kong, pp. 87-96 (2001).
• Cryopreservation of horseradish (Armoracia rusticana P. Gaert., B. Mey. et Scherb.) hairy root cultures
  Hirata, K., M. Phunchindawan, K. Miyamoto
  "Biotechnology in Agriculture and Forestry", Vol. 50, "Cryopreservation of Plant Germplasm II (edited by Y.P.S. Bajaj), Springer-Verlag, pp. 57-65 (2001).
• Phytochelatin synthetase: catalytic mechanism and acquisition of its function during molecular evolution
  Tsuji, N., K. Miyamoto, K. Hirata
  In Recent Res. Devel. Phytochem., Research Signpost, India, pp. 49-68 (2004).

 Publications

• Somrak Rodjaroen, Niran Juntawong, Aparat Mahakhant, Kazuhisa Miyamoto and Kasetsart J., High Biomass Production and Starch Accumulation in Native Green Algal Strains and Cyanobacterial Strains in Thailand. Nat. Sci. 41: 570-75 (2007).
• Environmentally friendly production of H₂ incorporating microalgal CO₂ fixation
  Ike, A., C. Saimura, K. Hirata, K. Miyamoto, J. Marine Biotechnol., 4, 47-51 (1996).
• Biological elimination of nitric oxide with carbon dioxide from flue gas by marine microalga NOA-113 cultivated in a long tubular photobioreactor
  Yoshihara, K., H. Nagase, K. Eguchi, K. Hirata, K. Miyamoto, J. Ferment. Bioeng., 82(4), 351-354 (1996).
• Novel violet pigment, nostocine A, an extracellular metabolite from cyanobacterium Nostoc spongiaeforme
  Hirata, K., H. Nakagami, J. Takashina, T. Mahmud, M. Kobayashi, Y. In, T. Ishida, K. Miyamoto, Heterocycles, 43(7), 1513-1519 (1996).
• Growth inhibition of various organisms by a violet pigment, nostocine A, produced by Nostoc spongiaeforme
  Hirata, K., J. Takashina, H. Nakagami, S. Ueyama, K. Murakami, T. Kanamori, K. Miyamoto, Biosci. Biotech. Biochem., 60(11), 1905-1906 (1996).
• Cryopreservation of microalgae using encapsulation-dehydration
  Hirata, K., M. Phunchindawan, J. Tukamoto, S. Goda, K. Miyamoto, Cryo-Letters, 17, 321-328 (1996).
• Removal of cadmium from aqueous solution by the filamentous cyanobacterium Tolypothrix tenuis
  Inthorn, D., H. Nagase, Y. Isaji, K. Hirata, K. Miyamoto, J. Ferment. Bioeng., 82(6), 580-584 (1996).
• Cryopreservation of encapsulated shoot primordia induced in horseradish (Armoracia rusticana) hairy root cultures
  Phunchindawan, M., K. Hirata, A. Sakai, K. Miyamoto, Plant Cell Reports, 16(7), 469-473 (1997).
• Non-enzymatic coupling of vindoline and catharanthine to synthesize 3',4'-anhydrovinblastine under irradiation with near-ultraviolet light
  Duangteraprecha, S., K. Hirata, E. Morihara, M. Nakae, H. Katayama, M. Honda, K. Miyamoto, J. Ferment. Bioeng., 83(3), 227-232 (1997).
• Biomimetic one-pot synthesis of vinblastine: NAD(P)H- mediated vinblastine synthesis from the product of FMN-mediated vindoline-catharanthine coupling under near-ultraviolet light
  Hirata, K., S. Duangteraprecha, E. Morihara, M. Honda, T. Akagi, M. Nakae, H. Katayama, K. Miyamoto, Biotechnol. Lett., 19(1), 53-57 (1997).
• Characteristics of biological NOx removal from flue gas in a Dunaliella tertiolecta culture system
  Nagase, H., K. Yoshihara, K. Eguchi, Y. Yokota, R. Matsui, K. Hirata, K. Miyamoto, J. Ferment. Bioeng., 83(5), 465-469 (1997).
• Selective cadmium removal from hard water using NaOH-treated cells of the cyanobacterium Tolypothrix tenuis
  Nagase, H., D. Inthorn, Y. Isaji, A. Oda, K. Hirata, K. Miyamoto, J. Ferment. Bioeng., 84(2), 151-154 (1997).
• Hydrogen photoproduction from CO₂ -fixing microalgal biomass: application of lactic acid fermentation by Lactobacillus amylovorus
  Ike, A., N. Toda, K. Hirata, K. Miyamoto, J. Ferment. Bioeng., 84(5), 411-416 (1997).
• Hydrogen photoproduction from CO₂ -fixing microalgal biomass: application of halotolerant photosynthetic bacteria
  Ike, A., N. Toda, N. Tsuji, K. Hirata, K. Miyamoto, J. Ferment. Bioeng., 84(6), 604-607 (1997).
• Cryopreservation of horseradish hairy root cultures by encapsulation-dehydration
  Hirata, K., S. Goda, M. Phunchindawan, D. Du, M. Ishio, A. Sakai, K. Miyamoto, J. Ferment. Bioeng., 86(4), 418-420 (1998).
• Improvement of microalgal NOx removal in bubble column and airlift reactors
  Nagase, H., K. Eguchi, K. Yoshihara, K. Hirata, K. Miyamoto, J. Ferment. Bioeng., 86(4), 421-423 (1998).
• Catharanthine oxidation in flavin mononucleotide-mediated catharanthine-vindoline coupling reaction for synthesis of dimeric indole alkaloids under near-ultraviolet light
  K. Hirata, T. Akagi, S. Duangteraprecha, M. Honda, Y. Sakamoto, H. Nagase, K. Miyamoto, J. Biosci. Bioeng., 87(6), 781-786 (1999).
• Photoproduction of hydrogen from raw starch using halophilic bacterial community
  Ike, A., T. Murakawa, H. Kawaguchi, K. Hirata, K. Miyamoto, J. Biosci. Bioeng., 88(1), 72-77 (1999).
• Rapid method for detection and detoxification of heavy metal ions in water environments using phytochelatin
  Satofuka, H., S. Amano, H. Atomi, M. Takagi, K. Hirata, K. Miyamoto, T. Imanaka, J. Biosci. Bioeng., 88(3), 287-292 (1999).
• Uptake pathway and continuous removal of nitric oxide from flue gas using microalgae
  Nagase, H., K. Yoshihara, K. Eguchi, Y. Okamoto, S. Murasaki, R. Yamashita, K. Hirata, K. Miyamoto, Biochem. Eng. J., 7(4), 241-246 (2001).
• H₂ production from algal biomass by a mixed culture of Rhodobium marinum A-501 and Lactobacillus amylovorus
  Kawaguchi, H., K. Hashimoto, K. Hirata, K. Miyamoto, J. Biosci. Bioeng., 91(3), 277-282 (2001).
• Utilization of cyanobacterial biomass from water bloom for bioproduction of lactic acid
  Susilaningsih, D., K. Hirata, Y. Asada, K. Miyamoto, World J. Microbiol. Biotechnol., 17(3), 259-264 (2001).
• Isolation and characterization of a bacterium that produces hydrocarbons extracellularly which are equivalent to light oil
  Park, M.-O., M. Tanabe, K. Hirata, K. Miyamoto, Appl. Microbiol. Biotechnol., 56(3-4), 448-452 (2001).
• Strong induction of phytochelatin synthesis by zinc in marine green alga, Dunaliella tertiolecta
  Hirata, K., Y. Tsujimoto, T. Namba, T. Ohta, N. Hirayanagi, H. Miyasaka, M.H. Zenk, K. Miyamoto, J. Biosci. Bioeng., 92(1), 24-29 (2001).
• Cellular toxicity of cadmium ions and their detoxification by heavy metal-specific plant peptides, phytochelatins, expressed in mammalian cells
  Takagi, M., H. Satofuka, S. Amano, H. Mizuno, Y. Eguchi, K. Hirata, K. Miyamoto, K. Fukui, T. Imanaka, J. Biochem., 131(2), 233-239 (2002).
• Cryopreservation of hairy root cultures of Vinca minor (L.) by encapsulation-dehydration}
  Hirata, K., M. Mukai, S. Goda, M. Ishio-Kinugasa, K. Yoshida, A. Sakai, K. Miyamoto, Biotechnol. Lett., 24(5), 371-376 (2002).
• Enhancement of tolerance to heavy metals and oxidative stress in Dunaliella tertiolecta by Zn-induced phytochelatin synthesis
  Tsuji, N. N. Hirayanagi, M. Okada, H. Miyasaka, K. Hirata, M. H. Zenk, K. Miyamoto, Biochem. Biophys. Res. Commun., 293(1), 653-659 (2002).
• Effect of algal extract on H₂ production by a photosynthetic bacterium Rhodobium marinum A-501: Analysis of stimulating effect by a kinetic model
  Kawaguchi, H., H. Nagase, K. Hashimoto, S. Kimata, M. Doi, K. Hirata, K. Miyamoto, J. Biosci. Bioeng., 94(1), 62-69 (2002).
• Regulation of phytochelatin synthesis by zinc and cadmium in marine green alga, Dunaliella tertiolecta
  Tsuji, N., N. Hirayanagi, O. Iwabe, T. Namba, M. Tagawa, S. Miyamoto, H. Miyasaka, M. Takagi, K. Hirata, K. Miyamoto, Phytochemistry, 62(3), 453-459 (2003).
• Removal of hazardous phenols by microalgae under photoautotrophic conditions
  Hirooka, T., Y. Akiyama, N. Tsuji, T. Nakamura, H. Nagase, K. Hirata, K. Miyamoto, J. Biosci. Bioeng., 95(2), 200-203 (2003).
• Photosynthesis-dependent removal of 2,4-dinitrophenol by Chlorella fusca var. vacuolata
  Tsuji, N., T. Hirooka, H. Nagase, K. Hirata, K. Miyamoto, Biotechnol. Lett., 25(3), 241-244 (2003).
• Induction of tolerance to oxidative stress in the green alga, Chlamydomonas reinhardtii, by abscisic acid
  Yoshida, K., E. Igarashi, M. Mukai, K. Hirata, K. Miyamoto, Plant Cell Environ., 26(3), 451-457 (2003).
• Bioactivities of nostocine A produced by freshwater cyanobacterium Nostic spongiaeforme TISTR 8169
  Hirata, K., S. Yoshitomi, S. Dwi, O. Iwabe, A. Mahakhant, J. Polchai, K. Miyamoto, J. Biosci. Bioeng., 95(5), 512-517 (2003).
• Ability of microbial consortium to remove pesticide, carbendazim and 2,4-dichlorophenoxyacetic acid
  Pattanasupong, A., H. Nagase, M. Inoue, K. Hirata, K. Tani, M. Nasu, K. Miyamoto, World J. Microbiol. Biotechnol., 20(5), 517-522 (2004).
• Degradation of carbendazim and 2,4-chlorophenoxyacetic acid by immobilized consortium on loofa sponge
  Pattanasupong, A., H. Nagase, E. Sugimoto, Y. Hori, K. Hirata, K. Tani, M. Nasu, K. Miyamoto, J. Biosci. Bioeng., 98(1), 28-33 (2004).
• Characterization of phytochelatin synthase-like protein encoded by alr0975 from a prokaryote, Nostoc sp. PCC7120
  Tsuji, N., S. Nishikori, O. Iwabe, K. Shiraki, H. Miyasaka, M. Takagi, K. Hirata, K. Miyamoto, Biochem. Biophys. Res. Commun., 315(3), 751-755 (2004).
• Generation of reactive oxygen species undergoing redox cycle of nostocine A, a cytotoxic violet pigment produced by freshwater cyanobacterium Nostoc spongiaeforme
  Hirata, K., S. Yoshitomi, S. Dwi, O. Iwabe, A. Mahakhant, J. Polchai., K. Miyamoto, J. Biotechnol., 110(1), 29-35 (2004).
• Functional analysis of phytochelatin synthase from Arabidopsis thaliana and its expression in Escherichia coli and Saccharomyces cerevisiae
  Matsumoto, S., K. Shiraki, N. Tsuji, K. Hirata, K. Miyamoto, M. Takagi, Science and Technology of Advanced Materials, 5(3), 377-381 (2004).
• Fluorescent probes for hydrogen peroxide based on a non-oxidative mechanism
  Maeda, H., Y. Fukuyasu, S. Yoshida, M. Fukuda, Y. Yamauchi, K. Yoshida, K. Hirata, K. Miyamoto, Angew. Chem., 116(18), 2443-2445 (2004).
• Abscisic acid induces suppression of generation of reactive oxygen species in Chlamydomonas reinhardtii exposed to water and heavy metal stresses
  Yoshida, K., E. Igarashi, E. Wakatsuki, K. Hirata, K. Miyamoto, Plant Sci., 167(6), 1335-1341 (2004).
• Evaluation of antimicrobial agents for veterinary use in the ecotoxicity test using microalgae
  Eguchi, K., H. Nagase, M. Ozawa, Y. S. Endo, K. Goto, K. Hirata, K. Miyamoto, H. Yoshimura, Chemosphere, 57(11), 1733-1738 (2004).
• Mitigation of osmotic and salt stresses by abscisic acid through reduction of stress-derived oxidative damage in Chlamydomonas reinhardtii.
  Yoshida, K., Igarashi, E., Wakatsuki, E., Miyamoto, K., Hirata, K.
  Plant Sci., 167, 1335-1341 (2004).
• Production of alternatives to fuel oil from organic waste by the alkane-producing bacterium, Vibrio furnissii M1.
  Park, M.-O., Heguri, K., Hirata, K., Miyamoto, K.
  J. Appl. Microbiol., 98, 324-331 (2005).
• Comparative analysis of the two-step reaction catalyzed by prokaryotic and eukaryotic phytochelatin synthase by an ion-pair liquid chromatography assay.
  Tsuji, N., Nishikori, S., Iwabe, O., Matsumoto, S., Shiraki, K., Miyasaka, H., Takagi, M., Miyamoto, K., Hirata, K.
  Planta, 222, 181-191 (2005).
• Biodegradation of bisphenol A and disappearance of its estrogenic activity by the green alga Chlorella fusca var. vacuolata.
  Hirooka, T., Nagase, H., Uchida, K., Hiroshige, Y., Ehara, Y., Nishikawa, J., Nishihara, T., Hirata, K., Miyamoto, K.
  Environ. Toxicol. Chem., 24, 1896-1902 (2005).
• Improvement of selective removal of heavy metals in cyanobacteria by NaOH-treatment.
  Nagase, H., Inthorn, D., Oda, A., Nishimura, J., Kajiwara, Y., Pak, M.-O., Hirata, K., Miyamoto, K.
  J. Biosci. Bioeng., 99, 272-277 (2005).
• Effect of environmental factors on performance of immobilized consortium system for degradation of carbendazim and 2,4-dichlorophenoxyacetic acid in continuous culture.
  Nagase, H., Pattanasupong, A., Sugimoto, E., Tani, K., Nasu, M., Hirata, K., Miyamoto, K.
  Biochem. Eng. J., 29, 157-162 (2006).
• Degradation of 2,4-dichlorophenol by mixed culture of photoautotrophic microorganisms.
  Hirooka, T., Nagase, H., Hirata, K., Miyamoto, K.
  Biochem. Eng. J., 29, 163-168 (2006).
• A novel method using cyanobacteria for ecotoxicity of veterinary antimicrobial agents
  Ando, T., Nagase, H., Eguchi K., Hirooka, K., Nakamura, T., Miyamoto, K., Hirata, K.
  Environ. Toxicol. Chem., 26, 601-606(2007)

 Presentations

• Growing the cyanobacterium Spirulina platensis in an artificial wastewater medium
  I Nyoman K. Kabinawa, Hiroyasu Nagase, Kazumasa Hirata, Kazuhisa Miyamoto, Annual Report of ICBiotech, 19, 403-409 (1996).
• Heavy metal removal from waste water by microalgae
  Miyamoto, K., A. Mahakhant, S. Dwi, D. Inthorn, H. Nagase, K. Hirata, Annual Report of ICBiotech, 20, 432-435 (1997).
• The protection and restoration of environments by microalgae
  Miyamoto, K., D. Inthorn, K. Yoshihara, H. Nagase, K. Hirata, Biotechnology for Sustainable Utilization of Biological Resources in the Tropics, 12, 196-201(1997).
• Application of green algae for clean environment -Removal of air pollutants and conversion of algal biomass to useful compounds-
  Hirata, K., H. Nagase, K. Miyamoto, Gratama Workshop 2000 Conference Report, pp.191-192 (2000).

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